Surface plasmon resonance spr is the resonant oscillation of conduction electrons at the interface between negative and positive permittivity material stimulated by incident lightspr is the basis of many standard tools for measuring adsorption of material onto planar metal typically gold or silver surfaces or onto the surface of metal nanoparticles. Surface plasmon resonance spr is a label free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions the technique makes it possible to measure interactions in real time with high sensitivity and without the need of labels. Surface plasmon resonance spr biosensors represent the most advanced label free optical affinity biosensor technology in the last decade numerous spr sensor platforms have been developed and . Surface plasmon resonance spr biosensors advances ji homola challenges and applications institute of photonics and electronics academy of sciences of the czech republic fjfi seminar november2010 established in 1954 over 150 staff members in three research divisions and support institute of photonics and electronics ufe units. Application note 19 using reicherts flexible surface plasmon resonance instrumentation for surface chemistry research application note 15 reichert spr epitope identification and affinity determination of horse heart myoglobin binding to myoglobin antibody by online spr ms
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